Research Department Nutrition and Food Sciences

Gregor-Mendel-Str. 2
85350 Freising

Tel.: 08161/ 71 - 2026
Fax: 08161/ 71 - 2824

email


Physiology of Human Nutrition

The unit follows two research lines: one is a gene guided approach in which the structure, function and biological importance of selected nutrient transport proteins is studied, the second lines is a systems biology approach to understand mammalian metabolism and adaptation by use of microarray, proteome and metabolome technologies. A large spectrum of model organism (E. coli, yeast, C. elegans, zebrafish, rats, mice) is available and used for comparative analysis of protein structure and functions. Human trials are performed to assess metabolic responses to dietary challenges and functional ingredients (i.e. zinc, polyphenols). There is considerable experience in analysis of gene expression with gene reporter assays/fusion proteins, immunohistochemistry and tissue culture studies, electrophysiology, laser scanning confocal microscopy, DNA microarray analysis, proteomics and MALDI-TOF-MS (peptide mass finger printing) and other analytical techniques for analysis of amino acids, intermediates, peptides and proteins, lipids (HPLC, LC-MS/MS).